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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54e755012d1831aac9c877724e5912a6bd0be002bd3ea6ee3111e2c449850f99' 
  AND token = 'FqW5d3JiNcwqM8iO3DS07s1yKAVZilxqn1vEFzhvLqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}