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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1223764d87fa94d083f6016fedca41d972191c548b3d15e6e87fff759b242e39' 
  AND token = 't7hHFOuNHTslFh5+bpYaXsD6qNua8P44eDzsNC6d+UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}