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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed1fd37fd7b62fa2d7fa57a0c9d995290b2dcd0638f85d91c104954a810015ff' 
  AND token = 'FAP6hrCsgthQ22+xi+UqCfn8p7c5T2C63jlfXSJ34+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}