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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b69f19365c12066013664c91afc06487c0fb3f59ab9ffb4bbaa639051c9ecec9' 
  AND token = 'AI6JvFpq5000c3egFBcixdHanSn5KAtV9R38thnBCis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}