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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7b6ce3ce32ea8d215dc6e71693901cb4a47d52023beb13d6846270f23044e14' 
  AND token = 'ADHELaCUCYu8e4O5hvZ8UG3YH7pNi7XjCSLhKSt1xw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}