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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4578c55c3372296c8f8a679b62cbea4745c26b903ee4ef867b0e10cb27a702' 
  AND token = 't6fhMXmZt68i0cIda8oxZ1kdPN4qwJm20wUZYnCZAnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}