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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0cee9e4b0d5f69ecbaab4f7b595b119210798466b71c060d33b06364c76fd4' 
  AND token = 'cG1S6Vb9RtR8BdfTuYZ3TtQ5Y8iBmNzBhlpFH0o1DOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}