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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a0d14356c147eb1cd24c83fd5715e1c1c0f5d849c8b6621e3fc890854308710' 
  AND token = 'I7HpEjAFnFkyGiVhr9K1s9x7Jhqv00LXI+OU+oswjtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}