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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7935610f3416d1ad962dc728e8da3e85d1b0dd14f9ca9d78f86af6a3e1e781' 
  AND token = 'H5KSzIUfdRMdDHUXHXsdwkiR+2txjIDFBLQillSS6Eo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}