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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4eeaec48582ee0cdc8273041c21d2717c6b6181e1c826ea89f43a0ee050800' 
  AND token = 'TtwlAIpDg4X+sT5OZ+CI9BNmtDFc6FRZ9kAAlGFE34E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}