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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '546a6ce731afbb2618f7c3767381e7d47b3d8b94416edaca06907d433a0a58d9' 
  AND token = 'x9lq6LG2d3fq5D15McpEAuNgi/h+a2Ju9jLCaoQcCpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}