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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c8bc07075d1519123759d8fe0dc79a8980c2029fa0527ed55ad3afc4c38473' 
  AND token = '1/ZZ9iXcslAc3XFtD5rYNx0grBfaTnNPksKucU45f0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}