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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e7eb29b499eec671af0b8133615004e9d577faf84191382e31bc9f9dabed733' 
  AND token = 'fduxEgH5MGXubS4wwnxIZN6Hd5jmLBVC3yd7aVWgDl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}