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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39e50eb89b37895274955babb8f1693aa4db0721d7b6dac4a35e584c0d0f4027' 
  AND token = 's7r3E947iB4bGa5s4TXlOSfLB35iE+GYma+eoe4Yegs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}