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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89738be4e2954a6389450fb181fb5d912ebc36b6df9fcc002cc43eb51d0bf409' 
  AND token = 'nc8AqaBYmeqO0SOU7FJsNMjn+yoXhv0GF0Hbv8o7ghY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}