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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58d3db2f5799c38bb4427220b4f1a71ebff5ba7a90440957d36a14f54cc10507' 
  AND token = 'k6gt0qIfRvd7DQxS/dFdhwY0RMzTvXxgmbfFX+dKT3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}