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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8793ab8f13709a5c70d1dcab9a3d0bc9edcc9b370987fa23f1f08d41b011d8cb' 
  AND token = 'ceJsaFRpeVm6CockGUJ7/fJ1U8UzBXqwfLjb6XAaM8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}