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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f033a7687be33f4cbe1a47792662ff5d1ef1bb7d1f394d0f75b0247815be33b8' 
  AND token = 'KBWf2TI/O9mNFbwV3xgPSV3fWnTT8dZ29/ikNUpOXwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}