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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53e2cf21362f331a1483b9777b8f40ac516717c2add6d6483ce8d588cd6bce3' 
  AND token = 'GpKMn5yGmGzV8nZ+m2M3LAtw2eFA+ESG03RGLXHHZxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}