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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580fc3a86a2f360b46570fb3826e2b2bc720225667c3727f0c42f12e82a96090' 
  AND token = '6f1G6zHsatP4Mw+VrXkyJbqQRuaBMaY4TRbJPXYHLa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}