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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f50a549f9b48d659d5601804222880f3a454a0aaa2c34a504ada3b42548ce403' 
  AND token = 'hFovMhbg51b1v/u9wPVpz4UJGthSOM0p1vVPKjlQrMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}