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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6a9fd5d49af9977e2264a091705f48fcaffb99df498b89e3cad1a6c4d72d7e' 
  AND token = 'Vk6fa3NpFzDao8WEv5uOLIlF9z8nzc3/vWetWWN3lmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}