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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6de8876a33a5fb70d4d40be76e47fdd60ab10f94d9fce25f7f56dcfa7afbc48' 
  AND token = 'cv30hQYwQfT7rBWu9RlU/+CDORlw+Rz+ygbN6PHstiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}