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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5644daaafc5215a89e3f1cd96971dc64f333f7be63e03e46e04610f49b7ecc21' 
  AND token = '3tJoDfWlRDOTcvtX3FbfDJYN1AfqiONlxJcyek8hXtg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}