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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357c54c8468f7c78b0e33c2fb2f99a0bf0891151968efb1b3e064e9af196104d' 
  AND token = '/sb8qJuLsNNYW1YwW5hQIY7tCX59b53Dlw/E5bGCgJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}