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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e86031394b74a97329ff920dc04cefa0eaa07323d6b0d4203b85592ae59e63c' 
  AND token = 'gZ44e9nlZY7Q3ifOqoG6iI+faSaZ/73U83R0ByJm+V4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}