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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd99a067466f989e54f4e90316dbcf09b431c88d0754df537d7114ea577c0a269' 
  AND token = 'E+Aruui0XhoqXEAo4aXHFVmtJGVPeOsagdserWkhvyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}