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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c81488307c35693b54136ae5565eed3df6d68cd34a787893c778012b23cd4be' 
  AND token = 'S84V2FUx1EQT929DBEUvr2H7FbwstE2THUjlnOpfeZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}