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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '531973fa2187583080bd586a10eb7b7a5c9fd69f948dbf1f2e3e81c1e54e7526' 
  AND token = 'R2Thvqe8e6wJHYM1fk//L0CIlfBQTZvo0qTCvm64mfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}