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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9e4f3dbc12e821e30f1b811272a7b0d5e251d381d6aadbed4252a839dce1a8f' 
  AND token = 'Kweb1D8SgTejQf/M4pnhWoSc8TueY7aHuZ5I2Ra5p3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}