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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bae8fbf2b201e8622180ae77694a145c8649be9e89de6d180c3672bee1daa57' 
  AND token = '4x+v3x3QJttDtXXL5jWrmEWzbJtV41aXzWqL8WzNxEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}