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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adf4c1395e7baa67a290603e56cf4cee6820dead5f8164d8710ce5b46687b135' 
  AND token = 'Kt8/5jQ7n6YDn6jqZBmePx5VComnEXd6rOfmHifOyM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}