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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7e53751438f0816f557effc4afa315f72de5a4aaee5145c76ec9947b9ae41cf' 
  AND token = 'zlc1/w6soePqvWWj51HLnemWuB9n+HGA1w8AxpgASm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}