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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff777a1934f47ac8ca05869cc97b7940fd51853e2e35455ff03f01798c4bee12' 
  AND token = 'f4SDcZaliLG4w7/cmK/cEavlDNnVcBoCEhJSAD0zcow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}