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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '477d68b7fc3cc8a22b45e2d0a320b1f84b23324cab1c55d44fe9581968b13db5' 
  AND token = 'nZz3bm32ls1bucKdSPObz+XYfw2jkvrVvvWiSMItorw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}