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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25730fbe0a2e0be5279ac14432f4a3edaf49c3d0baad6c154666484abd1a036' 
  AND token = 'dtZ4aEXXfoBEj9nbIRTQqu6dGTwi4bP++AWSatRYYns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}