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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd082ae494ed479ba66c0da5ad765d9312a99333ecebb2219eeeeeea65a55a41d' 
  AND token = 'opuQfwqQmYV2X3OXtdx/ZvmPIryGNnbGI5+J7sYmKyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}