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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e009ce7c8c8045037c81e52a08e0df49836652f888ede4a996513c088d04fae2' 
  AND token = 'PuP7czi1VGivjMAMikWRdGgMnssv3yh6upuUpakCgmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}