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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34416075958119349a07005a8a7c0db83eb88bbeb79241f4b9723b64a2c2d381' 
  AND token = 'pOtDQdsh/6w1HOa3Qo00Dm0EejCzP5K+BwqYMF09D1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}