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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73c294882cb1a90a220b0b3d0df2a3973eaa2779771b8525d73327abefb48703' 
  AND token = 'erdoS0MWT+PAu73xcQmZ/IQ28aHqc0fO3DxiDOM+JDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}