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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ddd48db1af02b3dd776af04836b0b4a3213dcf4db59b61a76f29e1f104de97a' 
  AND token = 'X5DWbiTlralH69IGfplT6CKvzjLhzFCEZjuBb69Ajg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}