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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '347945c6cee52809d2b01ae39a7c0a997c74eff578072373c21be969a356435c' 
  AND token = 'xDiGbp8G7OHopwu7R5PSfdNEQ80nE3CN0cB5CkkKDA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}