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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a4c996d59c6ca161bafc584a2d6d336c25c21914a4bdc24a5060ec73c790c5' 
  AND token = 'oObY8iijiY+Wdx4hpon/VgSXlIjahIkIpYvJ5oOpAvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}