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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38aaee7cb777c5066e753a2acc387a97e21086c0c5b72bd4287faa0605d7e5b5' 
  AND token = '5VU9WzUQdzKxWP/amtzPDMVITGfNuBPTrO5Baat5SMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}