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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b11aef0a9b8aa065bf1e7bdf3028b1d7a2a20af1b927186e090b20ce11212b63' 
  AND token = 'CzwpGjKGitfm+uv3Fmf8S3hX+UxF+nf8jp09zvjuFCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}