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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27eb033c3df526d5b4cc920a06aa6996c2e3589f5bf11b444ee463a99071fe9' 
  AND token = 'QW/8lf4zHqmP/dZZIlYwwSAO0l45/SEwxcjAEaQc7j0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}