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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f2773686d5fef00ea6547463e4ae33acdfd8323180da1138190b9b914b16b21' 
  AND token = 'oH2tA4WmyFQcu6Sgj0PfAdXQYWguo5gv95g97ZBOS5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}