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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ca53e6acf09fb891ca74874259079814da557d75115f5340e763e9a4389b8a' 
  AND token = 'GHxlwj/4uXSzN1IaTvmuqZk4S4cfaotQqCD83Yq4z9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}