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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e4b8a63dde368df10c45a7696fea64ecadac8848bf28cb6423b665bf735a24' 
  AND token = 'jQJ11h8GAcPagWZ5hfT7eI/t0AM0DPskIaQ9VR2te4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}