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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48137bfbc29174680ec482fe6809441b48de07860300a049fd1c7ec41a7a46d0' 
  AND token = 'DgLAKMxaB/jrqOi+oNAB61/MyCLm2YRT/IzLcFl28r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}